Using one-molecule optical and AFM imaging and pressure-spectroscopy strategies, we seek to unravel the mechanistic components of the framework and dynamics of chromosomes. Our study pursuits include things like:
1996, first mesoscopic cost density waves products; and initial electrical measurements on an individual metallic nanocluster in between nanoelectrodes
Round the very same time, the group of Paul McEuen, who was then centered with the University of California, Berkeley, confirmed comparable results on ropes of bundled nanotubes. Dependant upon the wrapping angle, nanotubes can are available in metallic or semiconducting variants, a prediction that we and Charles Lieber’s team at Harvard University independently verified employing scanning tunnelling spectroscopy experiments.
Non-equilibrium folding of individual DNA molecules recaptured as many as one thousand occasions inside of a reliable state nanopore
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Our analysis ranges through the biophysics of DNA to artificial cells and outside of. You should take a look down below in the spectrum of our existing assignments.
All parameters had been precisely the same for every panel During this online video, except for the Preliminary placement on the 6hb rod (demonstrated in blue) over the nanopore. Simulations that terminated early because of translocation in the rod throughout the pore are marked by a gray qualifications.
Nanopores symbolize a sublime and flexible Software to evaluate one molecules. We analysis novel detection modes with reliable-state nanopores and also various solutions to measure proteins with nanopores. Assignments encompass the subsequent:
‘You shouldn't just contemplate the inquiries of tomorrow, but in addition think about the questions of your working day following tomorrow’
Dekker commenced his research on solitary carbon nanotubes in 1993 when he set up a whole new line of research to review electrical transportation via solitary organic molecules ceesdekker.net amongst nanoelectrodes. In 1996 a breakthrough was understood with carbon nanotubes. This was accomplished in a very collaboration Using the team of Nobel laureate Richard Smalley. STM and nanolithography procedures have been utilized to demonstrate that these nanotubes are quantum wires at The only-molecule stage, with outstanding Bodily Houses.
An integrated microfluidic System for quantifying drug permeation across biomimetic vesicle membranes
2006, very first demonstration of molecular sorting in a lab on the chip working with biomotors; discovery of nanobubbles in reliable-state nanopores; and initially estimate of electrokinetic Power conversion within a nanofluidic channel
Electrical transport in monolayers of phthalocyanine molecular wires and AFM imaging of an individual wire bridging two electrodes
‘I am driven by ponder and issues. On a cloth level I discover solutions in physics, but I practical experience my deepest contentment with God. That religion also drives my science and how I cope with folks.